Vacations allow you to escape the routine of your everyday life. Making the most of your time away from home is up to you. If you’re interested in springing for once-in-a-lifetime hotel accommodations, here are a few unusual options.

Relax in Luxury
Looking to indulge beyond the traditional hotel and continental breakfast? A well-appointed retreat that makes you the focus can help you recharge your mind, body and spirit. One option: the art-centric Hotel Marques de Riscal in northern Spain, which was designed by renowned architect Frank Gehry and sits on an established vineyard of the same name.

Or you can add a little adventure to your luxury getaway. At Oberoi Vanyavilas in Ranthambore, India, guests can sip champagne from the observation tower and spot royal Bengal tigers at a nearby watering hole, along with other indigenous wildlife.

Travel off the Beaten Path
If a real escape sounds like music to your ears, consider a remote destination where you can avoid real-world interruptions. How about a quiet island retreat off the east coast of Africa? The Manta Resort on Zanzibar’s Pemba Island offers privacy and romance and the option to stay in an underwater room surrounded by untouched coral reefs and their inhabitants.

If that’s not remote enough, consider White Desert’s Whichaway Camp in Antarctica. From November through January, travelers can experience the South Pole and all of its beauty in comfort and style.

Go With What Speaks to You
Finding a one-of-a-kind stay isn’t as hard as you may imagine; just give some thought to your personal interests. Car enthusiast? The 4.5-star, auto-themed V8 Hotel in Stuttgart, Germany, may speak to you. Nature lover? Sleep among the clouds in one of the treetop rooms in Sweden’s aptly named Treehotel. Your options for unconventional lodging across the globe are nearly limitless.

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